PHARM 6220 - Pharmacokinetics & Pharmacodynamics

Basic principles of in-vivo drug kinetics (linear and non-linear); principles of bioavailability/bioequivalence; physiologic determinates of drug onset and duration; concepts of absorption, distribution, metabolism, and excretion; the pharmacokinetic-pharmacodynamic interface; dosage regimen design; renal and hepatic clearance; using pharmacodynamics to estimate drug half-life and adjust dosages.