BMI 6520 - Advanced Genetic Epidemiology: Linkage

An advanced, applied course for graduate students with a strong research focus on genetic epidemiology, and linkage analysis particularly. Provided sufficient demand, it is taught in the Spring semester. For additional information contact Dr. Nicola Camp. This course is structured as a mixture of lectures, analysis presentations, analysis discussions, paper debates, and computer and analysis labs. The course includes: data and file preparation; qualitative and quantitative traits; parametric and non-parametric analyses; theoretical aspects and practical analysis exercises of multiple genetic linkage methods; splitting pedigrees for analysis, ordered subset analysis, two-locus analysis; Monte-Carlo Markov-chain methods; sample size, power and significance and multiple testing issues.