PHCEU 7020 - Physical Chemistry of Biomedical and Drug Delivery Systems

Physicochemical fundamentals of dosage form design. Molecular thermodynamics approach to establishing principles of solutions, structures of liquids and solids, complexation, ion-solvent interactions, and multiple equilibria of organic solutes. Physicochemical examination of peptides and proteins, and protein structures. Thermodynamics of nucleic acids: temperature effects, cooperativity, and hybridization equilibria. Principles of colloid and interfacial sciences applied to pharmaceutical dosage formulations.