PATH 5050 - Mechanisms of Bacterial Pathogenesis

This course will provide an introduction to bacterial pathogenesis, with emphasis on molecular and genetic determinants of virulence. Topics will include: bacterial toxins, secretion systems and virulence, interaction with host defenses and immune evasion, genetic regulation and exchange of virulence determinants, tissue specific interaction with host receptors, the microbiome, antibiotics and resistance, vaccination, and bioterrorism.